Whilst it is well established that weight loss results in improvements in complications of obesity, there is minimal real-world data on the effectiveness of current treatments, particularly in the regional and remote context. At Royal Darwin Hospital, we established the first Weight Management Clinic in the NT designed to service both urban and remote residents of the NT. We aimed to determine whether such a service is effective and how it could be improved. A quarter of our clients are Aboriginal and Torres Strait Islander people, with 15% living remotely. This population differs from that in published efficacy trials, and therefore it is not clear that results from published studies are generalisable to our community. We determined the impact of the Weight Management Clinic on the health and wellbeing of people living with obesity attending the clinic (including efficacy, tolerability and side effects of treatments offered). We also determined patient satisfaction with the care provided through the clinic and patterns of patient attendance/non-attendance to the clinic. This has highlighted areas for improvement and resources required for the successful ongoing provision of a Weight Management Clinic.