Metabolic Syndrome is a group of conditions that increase the individual’s cardiovascular risk, and the components include obesity, hypertension, impaired glucose metabolism and dyslipidaemia. The clustering of the conditions within same individuals suggests a common pathophysiological process. The mineralocorticoid system is traditionally viewed as a regulator of blood pressure. This talk will discuss the novel role of the mineralocorticoid system in the pathophysiology of metabolic syndrome.